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ici 182780  (Tocris)


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    Structured Review

    Tocris ici 182780
    Ici 182780, supplied by Tocris, used in various techniques. Bioz Stars score: 96/100, based on 2330 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/ici+182780/ICI+182%2C780/pmc12900515-40-5-13
    Average 96 stars, based on 2330 article reviews
    ici 182780 - by Bioz Stars, 2026-09
    96/100 stars

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    Related Articles

    other:

    Article Title: Naoxintong Capsule Activates the Nrf2/HO-1 Signaling Pathway and Suppresses the p38α Signaling Pathway Via Estrogen Receptors to Ameliorate Heart Remodeling in Female Mice With Postmenopausal Hypertension
    Article Snippet: Limited treatments are available for alleviating heart remodeling in postmenopausal hypertension.. The cardioprotective effect of naoxintong (NXT) has been widely accepted.. This study aimed to explore the effects of NXT on pathological heart remodeling in a postmenopausal hypertension mouse model in vivo and H9c2 cardiomyocytes in vitro.

    Modification:

    Article Title: Effects of the Fertility Drugs Clomiphene Citrate and Letrozole on Kiss-1 Expression in Hypothalamic Kiss-1-Expressing Cell Models.
    Article Snippet: Clomiphene citrate (CC) and letrozole stimulate the hypothalamic-pituitary-ovarian axis and are used widely as oral fertility drugs to induce folliculogenesis.. We examined whether these drugs increase Kiss-1 expression in hypothalamic cell models.. We utilized two hypothalamic cell models, mHypoA-50 and mHypoA-55, which originated fromKiss-1 neurons in the anteroventral periventricular (AVPV) nucleus and arcuate (ARC) nucleus of the mouse hypothalamus, respectively.

    Membrane:

    Article Title: Effects of the Fertility Drugs Clomiphene Citrate and Letrozole on Kiss-1 Expression in Hypothalamic Kiss-1-Expressing Cell Models.
    Article Snippet: Clomiphene citrate (CC) and letrozole stimulate the hypothalamic-pituitary-ovarian axis and are used widely as oral fertility drugs to induce folliculogenesis.. We examined whether these drugs increase Kiss-1 expression in hypothalamic cell models.. We utilized two hypothalamic cell models, mHypoA-50 and mHypoA-55, which originated fromKiss-1 neurons in the anteroventral periventricular (AVPV) nucleus and arcuate (ARC) nucleus of the mouse hypothalamus, respectively.

    Concentration Assay:

    Article Title: Advancing fertility preservation in prepubertal mice: Efficacy of ovarian tissue culture and in vitro growth in mature oocyte development.
    Article Snippet: .. An estrogen receptor antagonist, ICI 182780 (ICI; Tocris Bioscience, Minneapolis, MN, USA), was added at a concentration of 10 μM. ..

    Injection:

    Article Title: Estrogen-sensitive activation of SGK1 induces M2 macrophages with anti-inflammatory properties and a Th2 response at the maternal–fetal interface
    Article Snippet: .. The mice were then regrouped again, and 60 mice were randomly divided into six groups with 10 mice in each group: (1) The E 2 group: OVX mice received daily intraperitoneal (IP) injections of corn oil containing E 2 (100 ng of E 2 in 100 μL of corn oil/mouse, E2758, Sigma-Aldrich, St. Louis, MO, USA) at 8:30 a.m. for 3 days [ ]. (2) The progesterone (P 4 ) group: OVX mice were injected with corn oil containing P 4 (1 mg of P 4 in 100 μL of corn oil/mouse, Cat. No. 2835, Tocris Bioscience, Bristol, UK) at 8:30 a.m. for 3 consecutive days [ ]. (3) The E 2 + P 4 group: OVX mice received daily IP injection of E 2 (100 ng of E 2 in 100 μL of corn oil/mouse) at 8:30 a.m. for 2 days, and then were treated with P 4 (1 mg of P 4 in 100 μL of corn oil/mouse) by IP injection at 8:30 a.m. on the 3rd day [ ]. (4) The ICI 182780 group: female mice with intact ovaries received IP injection of ICI 182780 (an estrogen receptor antagonist, 100 μg/mouse, Cat. No. 1047, Tocris Bioscience) at 08:30 a.m. on the first day [ ]. (5) OVX control group: OVX mice were injected with corn oil (100 μL corn oil/mouse, 8001–30-7, Picasso-e, Shanghai, China) alone for 3 consecutive days. (6) Sham group: female mice with intact ovaries; all mice were euthanized by cervical dislocation at 6:00 p.m. on Day 3. ..

    Article Title: Estrogen-sensitive activation of SGK1 induces M2 macrophages with anti-inflammatory properties and a Th2 response at the maternal-fetal interface.
    Article Snippet: .. The mice were then regrouped again, and 60 mice were randomly divided into six groups with 10 mice in each group: (1) The E2 group: OVX mice received daily intraperitoneal (IP) injections of corn oil containing E2 (100 ng of E2 in 100 μL of corn oil/mouse, E2758, Sigma-Aldrich, St. Louis, MO, USA) at 8:30 a.m. for 3 days [39]. (2) The progesterone (P4) group: OVX mice were injected with corn oil containing P4 (1 mg of P4 in 100 μL of corn oil/mouse, Cat. No. 2835, Tocris Bioscience, Bristol, UK) at 8:30 a.m. for 3 consecutive days [40]. (3) The E2 + P4 group: OVX mice received daily IP injection of E2 (100 ng of E2 in 100 μL of corn oil/mouse) at 8:30 a.m. for 2 days, and then were treated with P4 (1 mg of P4 in 100 μL of corn oil/mouse) by IP injection at 8:30 a.m. on the 3rd day [38]. (4) The ICI 182780 group: female mice with intact ovaries received IP injection of ICI 182780 (an estrogen receptor antagonist, 100 μg/ mouse, Cat. No. 1047, Tocris Bioscience) at 08:30 a.m. on the first day [41]. (5) OVX control group: OVX mice were injected with corn oil (100 μL corn oil/mouse, 8001–30- 7, Picasso-e, Shanghai, China) alone for 3 consecutive days. (6) Sham group: female mice with intact ovaries; all mice were euthanized by cervical dislocation at 6:00 p.m. on Day 3. ..

    Control:

    Article Title: Estrogen-sensitive activation of SGK1 induces M2 macrophages with anti-inflammatory properties and a Th2 response at the maternal–fetal interface
    Article Snippet: .. The mice were then regrouped again, and 60 mice were randomly divided into six groups with 10 mice in each group: (1) The E 2 group: OVX mice received daily intraperitoneal (IP) injections of corn oil containing E 2 (100 ng of E 2 in 100 μL of corn oil/mouse, E2758, Sigma-Aldrich, St. Louis, MO, USA) at 8:30 a.m. for 3 days [ ]. (2) The progesterone (P 4 ) group: OVX mice were injected with corn oil containing P 4 (1 mg of P 4 in 100 μL of corn oil/mouse, Cat. No. 2835, Tocris Bioscience, Bristol, UK) at 8:30 a.m. for 3 consecutive days [ ]. (3) The E 2 + P 4 group: OVX mice received daily IP injection of E 2 (100 ng of E 2 in 100 μL of corn oil/mouse) at 8:30 a.m. for 2 days, and then were treated with P 4 (1 mg of P 4 in 100 μL of corn oil/mouse) by IP injection at 8:30 a.m. on the 3rd day [ ]. (4) The ICI 182780 group: female mice with intact ovaries received IP injection of ICI 182780 (an estrogen receptor antagonist, 100 μg/mouse, Cat. No. 1047, Tocris Bioscience) at 08:30 a.m. on the first day [ ]. (5) OVX control group: OVX mice were injected with corn oil (100 μL corn oil/mouse, 8001–30-7, Picasso-e, Shanghai, China) alone for 3 consecutive days. (6) Sham group: female mice with intact ovaries; all mice were euthanized by cervical dislocation at 6:00 p.m. on Day 3. ..

    Article Title: Estrogen-sensitive activation of SGK1 induces M2 macrophages with anti-inflammatory properties and a Th2 response at the maternal-fetal interface.
    Article Snippet: .. The mice were then regrouped again, and 60 mice were randomly divided into six groups with 10 mice in each group: (1) The E2 group: OVX mice received daily intraperitoneal (IP) injections of corn oil containing E2 (100 ng of E2 in 100 μL of corn oil/mouse, E2758, Sigma-Aldrich, St. Louis, MO, USA) at 8:30 a.m. for 3 days [39]. (2) The progesterone (P4) group: OVX mice were injected with corn oil containing P4 (1 mg of P4 in 100 μL of corn oil/mouse, Cat. No. 2835, Tocris Bioscience, Bristol, UK) at 8:30 a.m. for 3 consecutive days [40]. (3) The E2 + P4 group: OVX mice received daily IP injection of E2 (100 ng of E2 in 100 μL of corn oil/mouse) at 8:30 a.m. for 2 days, and then were treated with P4 (1 mg of P4 in 100 μL of corn oil/mouse) by IP injection at 8:30 a.m. on the 3rd day [38]. (4) The ICI 182780 group: female mice with intact ovaries received IP injection of ICI 182780 (an estrogen receptor antagonist, 100 μg/ mouse, Cat. No. 1047, Tocris Bioscience) at 08:30 a.m. on the first day [41]. (5) OVX control group: OVX mice were injected with corn oil (100 μL corn oil/mouse, 8001–30- 7, Picasso-e, Shanghai, China) alone for 3 consecutive days. (6) Sham group: female mice with intact ovaries; all mice were euthanized by cervical dislocation at 6:00 p.m. on Day 3. ..



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